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Biologie Epidémiologie et Analyse de Risque en santé animale

BIOEPAR - http://www6.angers-nantes.inra.fr/bioepar

Malandrin Laurence

Equipe "Ticks and tick-Borne Diseases"

Laurence Malandrin
© LM
Chargé de Recherche INRA
Contact

Email : laurence (point) malandrin (at) oniris-nantes (point) fr
Tél : 02 40 68 78 57
Fax : 02 40 68 77 51

Diplômes
  • 2011 : Habilitation à diriger des recherches
  • 2000 à nos jours : Chargée de Recherche INRA
  • Post-doctorat 2000. "Quorum sensing et déclenchement des facteurs de virulence chez les E. coli EPEC". Université de Nottingham, Angleterre
  • Post-doctorat 1997-2000. "Le cycle cellulaire des Archaea hyperthermophiles". Biomedical Centre, Université d'Uppsala, Suède
  • Post-doctorat 1996 INA-PG. "Les facteurs de pathogénicité chez Erwinia amylovora"
  • Doctorat de Microbiologie 1992-1995. Réalisé à l'INRA d' Angers "Les protéines de surface de Pseudomonas syringae (sensu lato). Description, variabilité et application taxonomique". Thèse de l'Université d'Angers
  • Bourse de mobilité européenne Marie Curie 1992. Federal Biological Research Centre for Agriculture and Forestry, Brunswick, Allemagne
  • DEA 1991. "Sciences et Techniques des Productions Végétales et Alimentaires". Université de Nantes, France
Thèmes de recherche
  • Babesia
  • Maladies transmises par les tiques
  • Zoonoses
  • Interactions Babesia - globule rouge : le processus d'invasion
  • Diversité génétique et description taxonomique d'espèces
  • Interactions Babesia - tiques
  • Élevages de tiques saines
  • Spécificité d'hôtes
Thèmes d'enseignement
  • Les Apicomplexes : interactions avec leur cellule hôte
  • Biologie moléculaire
Responsabilités
  • Membre de la Société Française de Parasitologie
  • Expert auprès de l'ANSES (évaluation scientifique 2012)
  • Expert auprès de l'AERES
  • Contributions de relecture pour les revues scientifiques : PlosOne - International Journal for Parasitology - Tick and Tick-borne Diseases - Vector-borne and Zoonotic diseases - Veterinary Parasitology - Parasite
Liens

http://www.researchgate.net/profile/Laurence_Malandrin

Publications
  • Jalovecka M., Hajdusek O., Sojka D., Kopacek P., Malandrin L. 2018. The Complexity of Piroplasms Life Cycles. Frontiers in Cellular and Infection Microbiology, 8(248). [IF17=3.520] DOI: 10.3389/fcimb.2018.00248.
  • Sertour N., Cotté V., Garnier M., Malandrin L., Ferquel E., Choumet V. 2018. Infection Kinetics and Tropism of Borrelia burgdorferi sensu lato in Mouse After Natural (via Ticks) or Artificial (Needle) Infection Depends on the Bacterial Strain. Frontiers in Microbiology, 9(1722). [IF17=4.019] DOI: 10.3389/fmicb.2018.01722.
  • Jouglin M., Chagneau S., Faille F., Verheyden H., Bastian S., Malandrin L. 2017. Detecting and characterizing mixed infections with genetic variants of Anaplasma phagocytophilum in roe deer (Capreolus capreolus) by developing an ankA cluster-specific nested PCR. Parasites & Vectors, 10(1):377. [IF17=3.163] DOI: 10.1186/s13071-017-2316-0.
  • Jouglin M., Perez G., Butet A., Malandrin L., Bastian S. 2017. Low prevalence of zoonotic Babesia in small mammals and Ixodes ricinus in Western France. Veterinary Parasitology, 238:58-60. [IF17=2.422] DOI:        10.1016/j.vetpar.2017.03.020.
  • Jalovecka M., Bonsergent C., Hajdusek O., Kopacek P., Malandrin L. 2016. Stimulation and quantification of Babesia divergens gametocytogenesis. Parasites & Vectors, 9(1):439. [IF17=3.163] DOI: 10.1186%2Fs13071-016-1731-y.
  • Niu Q., Bonsergent C., Rogniaux H., Guan G., Malandrin L., Moreau E. 2016. RAP-1a is the main rhoptry-associated-protein-1 (RAP-1) recognized during infection with Babesia sp. BQ1 (Lintan) (B. motasi-like phylogenetic group), a pathogen of sheep in China. Veterinary Parasitology, 232:48-57. [IF17=2.422] DOI: 10.1016/j.vetpar.2016.11.013.
  • Lempereur L., Shiels B., Heyman A., Moreau E., Saegerman C., Losson B., Malandrin L. 2015. A retrospective serological survey on human babesiosis in Belgium. Clinical Microbiology and Infection 21(1):96.e91-96.e97. [IF17=5.394] DOI: 10.1016/j.cmi.2014.07.004.
  • Moreau E., Bonsergent C., Al Dybiat I., Gonzalez L. M., Lobo C. A., Montero E., Malandrin L. 2015. Babesia divergens apical membrane antigen-1 (BdAMA-1): A poorly polymorphic protein that induces a weak and late immune response. Experimental Parasitology 155:40-45. [IF17=1.821] DOI: 10.1016/j.exppara.2015.04.024.
  • Niu Q., Marchand J., Yang C., Bonsergent C., Guan G., Yin H., Malandrin L. 2015. Rhoptry-Associated-Protein (RAP-1) genes in the sheep pathogen Babesia sp. Xinjiang: multiple copies differing by 3' end repeated sequences. Veterinary Parasitology 211(3-4):158-169. [IF17=2.422] DOI: 10.1016/j.vetpar.2015.04.030.
  • Cotté V., Sabatier L., Schnell G., Carmi-Leroy A., Rousselle J.-C., Arsène-Ploetze F., Malandrin L., Sertour N., Namane A., Ferquel E., Choumet V. 2014. Differential expression of Ixodes ricinus salivary gland proteins in the presence of the Borrelia burgdorferi sensu lato complex. Journal of Proteomics 96, 29-43 [IF17=3.722]. DOI: 10.1016/j.jprot.2013.10.033.
  • Jackson A.P., Otto T.D., Darby A., Ramaprasad A., Xia D., Echaide I.E., Farber M., Gahlot S., Gamble J., Gupta D., Gupta Y., Jackson L., Malandrin L., Malas T.B., Moussa E., Nair M., Reid A.J., Sanders M., Sharma J., Tracey A., Quail M.A., Weir W., Wastling J.M., Hall N., Willadsen P., Lingelbach K., Shiels B., Tait A., Berriman M., Allred D.R., Pain A. 2014. The evolutionary dynamics of variant antigen genes in Babesia reveal a history of genomic innovation underlying host–parasite interaction. Nucleic Acids Research 42(11):7113-7131 [IF17=11.561]. DOI: 10.1093/nar/gku322.
  • Jouglin M., Fernandez-de-Mera I., De la Cotte N., Ruiz-Fons F., Gortazar C., Moreau E., Bastian S., de la Fuente J., Malandrin L. 2014. Isolation and characterization of Babesia pecorum sp. nov. from farmed red deer (Cervus elaphus). Veterinary Research 45(1):78 [IF17=2.903]. DOI: 10.1186/s13567-014-0078-7.
  • Niu Q., Valentin C., Bonsergent C., Malandrin L. 2014. Strong conservation of rhoptry-associated-protein-1 (RAP-1) locus organization and sequence among Babesia isolates infecting sheep from China (Babesia motasi-like phylogenetic group). Infection Genetics and Evolution 28, 21-32 [IF17=2.545]. DOI: 10.1016/j.meegid.2014.08.028.
  • Becker C. A. M., Malandrin L., Larcher T., Chauvin A., Bischoff E., Bonnet S. I. 2013. Validation of BdCCp2 as a marker for Babesia divergens sexual stages in ticks. Experimental Parasitology 133(1):51-56 [IF17=1.821]. DOI: 10.1016/j.exppara.2012.10.007.
  • Niu Q., Bonsergent C., Guan G. Q., Yin H., Malandrin L. 2013. Sequence and organization of the rhoptry-associated-protein-1 (rap-1) locus for the sheep hemoprotozoan Babesia sp. BQ1 Lintan (B. motasi phylogenetic group). Veterinary Parasitology 198(1-2):24-38 [IF17=2.422]. DOI: 10.1016/j.vetpar.2013.08.025.
  • Agoulon A., Malandrin L., Lepigeon F., Vénisse M., Bonnet S., Becker C. A. M., Hoch T., Bastian S., Plantard O., Beaudeau F. 2012. A Vegetation Index qualifying pasture edges is related to Ixodes ricinus density and to Babesia divergens seroprevalence in dairy cattle herds. Veterinary Parasitology, 185(2-4):101-109 [IF17=2.422] DOI: 10.1016/j.vetpar.2011.10.022.
  • Bastian S., Jouglin M., Brisseau N., Malandrin L., Klegou G., L’Hostis M., Chauvin A. 2012. Antibody prevalence and molecular identification of Babesia spp. in roe deer in France. Journal of Wildlife Diseases 48(2):416-424 [IF17=1.247]. DOI: 10.7589/0090-3558-48.2.416.
  • Hoch T., Goebel J., Agoulon A., Malandrin L. 2012. Modelling bovine babesiosis: A tool to simulate scenarios for pathogen spread and to test control measures for the disease. Preventive Veterinary Medicine 106(2):136-142 [IF17=1.924] DOI: 10.1016/j.prevetmed.2012.01.018.
  • Sun Y., Jouglin M., Bastian S., Chauvin A., Malandrin L. 2011. Molecular cloning and genetic polymorphism of Babesia capreoli gene Bcp37/41, an ortholog of Babesia divergens merozoite surface antigen Bd37. Veterinary Parasitology 178(1-2):184-191 [IF17=2.422]. DOI: 10.1016/j.vetpar.2010.12.021.
  • Sun Y., Moreau E., Chauvin A., Malandrin L. 2011. The invasion process of bovine erythrocyte by Babesia divergens: knowledge from an in vitro assay. Veterinary Research 42:62 [IF17=2.903]. DOI: 10.1186/1297-9716-42-62.
  • Becker C.A.M., Malandrin L., Depoix D., David P.H., Chauvin A., Bischoff E., Bonnet S. 2010. Identification of three CCp genes in Babesia divergens: novel markers for sexual stages parasites. Molecular and Biochemical Parasitology 174(1):36-43 [IF17=1.744] DOI: 10.1016/j.molbiopara.2010.06.011.
  • Malandrin L., Jouglin M., Sun Y., Brisseau N., Chauvin A. 2010. Redescription of Babesia capreoli (Enigk and Friedhoff, 1962) from roe deer (Capreolus capreolus): Isolation, cultivation, host specificity, molecular characterisation and differentiation from Babesia divergens. International Journal for Parasitology 40(3):277-284 [IF17=3.078] DOI: 10.1016/j.ijpara.2009.08.008.

 

Voir aussi

Les publications de Laurence Malandrin dans ProdINRA