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INRA
24, chemin de Borde Rouge –Auzeville – CS52627
31326 Castanet Tolosan CEDEX - France

Dernière mise à jour : Mai 2018

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Laurence Malandrin

Équipe VIP

Laurence Malandrin
© LM
Chargé de Recherche INRA Animateur équipe VIP
Coordonnées

ONIRIS - Ecole nationale vétérinaire, agroalimentaire et de l'alimentation Nantes-Atlantique
Site de la Chantrerie - CS 40706
44307 Nantes cedex 03
Email : laurence (point) malandrin (at) oniris-nantes (point) fr
Tél : 02 40 68 78 57
Fax : 02 40 68 77 51

Responsabilités
  • Animateur de l'équipe VIP
Département de recherche

Santé Animale

Diplômes
  • 2011 : Habilitation à diriger des recherches
  • 2000 à nos jours : Chargée de Recherche INRA
  • Post-doctorat 2000. "Quorum sensing et déclenchement des facteurs de virulence chez les E. coli EPEC". Université de Nottingham, Angleterre
  • Post-doctorat 1997-2000. "Le cycle cellulaire des Archaea hyperthermophiles". Biomedical Centre, Université d'Uppsala, Suède
  • Post-doctorat 1996 INA-PG. "Les facteurs de pathogénicité chez Erwinia amylovora"
  • Doctorat de Microbiologie 1992-1995. Réalisé à l'INRA d' Angers "Les protéines de surface de Pseudomonas syringae (sensu lato). Description, variabilité et application taxonomique". Thèse de l'Université d'Angers
  • Bourse de mobilité européenne Marie Curie 1992. Federal Biological Research Centre for Agriculture and Forestry, Brunswick, Allemagne
  • DEA 1991. "Sciences et Techniques des Productions Végétales et Alimentaires". Université de Nantes, France
Thèmes de recherche
  • Babesia
  • Maladies transmises par les tiques
  • Zoonoses
  • Interactions Babesia - globule rouge : le processus d'invasion
  • Diversité génétique et description taxonomique d'espèces
  • Interactions Babesia - tiques
  • Élevages de tiques saines
  • Spécificité d'hôtes
Thèmes d'enseignement
  • Les Apicomplexes : interactions avec leur cellule hôte
  • Biologie moléculaire
Responsabilités
  • Animateur de l'équipe VIP de l'UMR BioEpAR
  • Membre de la Société Française de Parasitologie
  • Expert auprès de l'ANSES (évaluation scientifique 2012)
  • Expert auprès de l'AERES
  • Contributions de relecture pour les revues scientifiques : PlosOne - International Journal for Parasitology - Tick and Tick-borne Diseases - Vector-borne and Zoonotic diseases - Veterinary Parasitology - Parasite
Publications
  • Lempereur L., Shiels B., Heyman A., Moreau E., Saegerman C., Losson B., Malandrin L., 2015. A retrospective serological survey on human babesiosis in Belgium. Clinical Microbiology and Infection 21(1):96.e91-96.e97 [IF13=5.197]. DOI: 10.1016/j.cmi.2014.07.004.
  • Cotté V., Sabatier L., Schnell G., Carmi-Leroy A., Rousselle J.-C., Arsène-Ploetze F., Malandrin L., Sertour N., Namane A., Ferquel E., Choumet V., 2014. Differential expression of Ixodes ricinus salivary gland proteins in the presence of the Borrelia burgdorferi sensu lato complex. Journal of Proteomics 96, 29-43 [IF13=3.929]. DOI: 10.1016/j.jprot.2013.10.033.
  • Jackson A.P., Otto T.D., Darby A., Ramaprasad A., Xia D., Echaide I.E., Farber M., Gahlot S., Gamble J., Gupta D., Gupta Y., Jackson L., Malandrin L., Malas T.B., Moussa E., Nair M., Reid A.J., Sanders M., Sharma J., Tracey A., Quail M.A., Weir W., Wastling J.M., Hall N., Willadsen P., Lingelbach K., Shiels B., Tait A., Berriman M., Allred D.R., Pain A., 2014. The evolutionary dynamics of variant antigen genes in Babesia reveal a history of genomic innovation underlying host–parasite interaction. Nucleic Acids Res. 42(11):7113-7131 [IF13=8.808]. DOI: 10.1093/nar/gku322.
  • Jouglin M., Fernandez-de-Mera I., De la Cotte N., Ruiz-Fons F., Gortazar C., Moreau E., Bastian S., de la Fuente J., Malandrin L., 2014. Isolation and characterization of Babesia pecorum sp. nov. from farmed red deer (Cervus elaphus). Vet. Res. 45(1):78 [IF13=3.383]. DOI: 10.1186/s13567-014-0078-7.
  • Niu Q., Valentin C., Bonsergent C., Malandrin L., 2014. Strong conservation of rhoptry-associated-protein-1 (RAP-1) locus organization and sequence among Babesia isolates infecting sheep from China (Babesia motasi-like phylogenetic group). Infect. Genet. Evol. 28, 21-32 [IF13=3.264]. DOI: 10.1016/j.meegid.2014.08.028.
  • Becker C. A. M., Malandrin L., Larcher T., Chauvin A., Bischoff E., Bonnet S. I., 2013. Validation of BdCCp2 as a marker for Babesia divergens sexual stages in ticks. Exp. Parasitol., 133(1):51-56 [IF13=1.859]. DOI: 10.1016/j.exppara.2012.10.007.
  • Niu Q., Bonsergent C., Guan G. Q., Yin H., Malandrin L. 2013. Sequence and organization of the rhoptry-associated-protein-1 (rap-1) locus for the sheep hemoprotozoan Babesia sp. BQ1 Lintan (B. motasi phylogenetic group). Vet. Parasitol. 198(1-2):24-38 [IF13=2.545]. DOI: 10.1016/j.vetpar.2013.08.025.
  • Agoulon A., Malandrin L., Lepigeon F., Vénisse M., Bonnet S., Becker C. A. M., Hoch T., Bastian S., Plantard O., Beaudeau F. 2012. A Vegetation Index qualifying pasture edges is related to Ixodes ricinus density and to Babesia divergens seroprevalence in dairy cattle herds. Vet. Parasitol., 185(2-4):101-109 [IF12=2.381] DOI: 10.1016/j.vetpar.2011.10.022.
  • Bastian S., Jouglin M., Brisseau N., Malandrin L., Klegou G., L’Hostis M., Chauvin A., 2012. Antibody prevalence and molecular identification of Babesia spp. in roe deer in France. J. Wildl. Dis., 48(2):416-424 [IF13=1.305]. DOI: 10.7589/0090-3558-48.2.416.
  • Hoch T., Goebel J., Agoulon A., Malandrin L. 2012. Modelling bovine babesiosis: A tool to simulate scenarios for pathogen spread and to test control measures for the disease. Prev. Vet. Med., 106(2):136-142 [IF12=2.389] DOI: 10.1016/j.prevetmed.2012.01.018.
  • Sun Y., Jouglin M., Bastian S., Chauvin A., Malandrin L. 2011. Molecular cloning and genetic polymorphism of Babesia capreoli gene Bcp37/41, an ortholog of Babesia divergens merozoite surface antigen Bd37. Vet. Parasitol. 178(1-2):184-191 [IF13=2.545]. DOI: 10.1016/j.vetpar.2010.12.021.
  • Sun Y., Moreau E., Chauvin A., Malandrin L. 2011. The invasion process of bovine erythrocyte by Babesia divergens: knowledge from an in vitro assay. Vet. Res. 42:62 [IF13=3.383]. DOI: 10.1186/1297-9716-42-62.
  • Becker C.A.M., Malandrin L., Depoix D., David P.H., Chauvin A., Bischoff E., Bonnet S. 2010. Identification of three CCp genes in Babesia divergens: novel markers for sexual stages parasites. Mol. Biochem. Parasitol. 174(1):36-43 [IF13=2.243] DOI: 10.1016/j.molbiopara.2010.06.011.
  • Malandrin L., Jouglin M., Sun Y., Brisseau N., Chauvin A. 2010. Redescription of Babesia capreoli (Enigk and Friedhoff, 1962) from roe deer (Capreolus capreolus): Isolation, cultivation, host specificity, molecular characterisation and differentiation from Babesia divergens. Int. J. Parasitol. 40(3):277-284 [IF13=3.404] DOI: 10.1016/j.ijpara.2009.08.008.

 

Voir aussi

Les publications de Laurence Malandrin dans ProdINRA