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Publications & COV


  • Avelange-Macherel MH, Candat A, Neveu M, Tolleter D, Macherel D. (2018) Decoding the divergent subcellular location of two highly similar paralogous LEA proteins. International Journal of Molecular Sciences, 19: 1620.
  • Cukier C, Lea PJ, Cañas R, Marmagne A, Limami AM, Hirel B. (2018) Labeling maize (Zea mays L.) leaves with 15 NH4+ and monitoring nitrogen incorporation into amino acids by GC/MS analysis. Current Protocols in Plant Biology,
  • Le Moigne MA, Guérin V, Furet PM, Billard V, Lebrec A, Spichal L, Roman H, Citerne S, Morvan-Bertrand A, Limami AM, Vian A, Lothier J. (2018) Asparagine and sugars are both required to sustain secondary axis elongation after bud outgrowth in Rosa hybrida. Journal of Plant Physiology, 222: 17-27.
  • Planchet E, Lothier J, Limami AM. (2018) Hypoxic respiratory metabolism in plants: reorchestration of nitrogen and carbon metabolisms. In Plant respiration : metabolic fluxes and carbon balance, Advances in photosynthesis and respiration (Eds: Terchkez G, Ghashghaie J.), Springer International Publishing, 43: 209-226.
  • Pontié M, Jaspard E, Papon N, Bouchara J-P, Razafimandimby B, Pillet A, Wang X, Friant C, Mbokou S, Vautrin-Ul C, Chelaghmia M. (2018) Enhanced direct oxidation of diclofenac (DCF) at a carbon paste electrode (CPE) modified with cellulose and its biodegradability by Scedosporium dehoogii. Research and Reviews in Electrochemistry, 9: 114-128.
  • Satour P, Youssef C, Châtelain E, Ly Vu B, Teulat B, Job C, Job D, Montrichard F. (2018) Patterns of protein carbonylation during Medicago truncatula seed maturation. Plant Cell & Environment, doi: 10.1111/pce.13194.


  • Bosseno M, Lambert A, Beucher D, Aubry C, Le Gleuher M, Pauly N, Montrichard F, Boscari A. (2017) Protocole simple de rétrocroisement chez Medicago truncatula. Le Cahier des Techniques de l’INRA (92).
  • Cañas RA, Yesbergenova-Cuny Z, Simons M, Chardon F, Armengaud P, Quilleré I, Cukier C, Gibon Y, Limami AM, Nicolas SD, Brulé L, Lea PJ, Maranas CD, Hirel B (2017) Exploiting the genetic diversity of maize using a combined metabolomic, enzyme activity profiling, and metabolic modelling approach to link leaf physiology to kernel yield. Plant Cell, 29: 919-943.
  • Castella C, Mirtziou I, Seassau A, Boscari A, Montrichard F, Papadopoulou K, Rouhier N, Puppo A, Brouquisse R. (2017) Post-translational modifications of Medicago truncatula glutathione peroxidase 1 induced by nitric oxide. Nitric Oxide, 68: 125-136.
  • Paszkiewicz G, Gualberto JM, Benamar A,   Macherel D, Logan DC (2017) Arabidopsis seed mitochondria are bioenergetically active immediately upon imbibition and specialize via biogenesis in preparation for autotrophic growth. The Plant Cell, 29, 109-128.
  • Pellizzaro A, Alibert B, Planchet E, Limami AM, Morère-Le Paven MC (2017) Nitrate transporters : an overview in legumes. Planta, 246: 585-595.
  • Péron T, Candat A, Montiel G, Veronesi C, Macherel D, Delavault P, Simier P (2017) New insights into phloem unloading and expression of sucrose transporters in vegetative sinks of the parasitic plant Phelipanche ramosa L. (Pomei). Frontiers in Plant Science, 7, 2048.
  • Raveneau MP, Benamar A, Macherel D (2017) Water content, adenylate kinase, and mitochondria drive adenylate balance in dehydrating and imbibing seeds. Journal of Experimental Botany, 68, 3501-3512.
  • Ribeiro CW, Baldacci-Cresp F, Pierre O, Larousse M, Benyamina S, Lambert A, Hopkins J, Castella C, Cazareth J, Alloing G, Boncompagni E, Couturier J, Mergaert P, Gamas P, Rouhier N, Montrichard F, Frendo P (2017) Regulation of differentiation of nitrogen-fixing bacteria by microsymbiont targeting of plant thioredoxin s1. Current Biology, 27: 1-7.
  • Wakim J, Goudenege D, Perrot R, Gueguen N, Desquiret-Dumas V, Chao de la Barca JM, Rosa ID, Manero F,Le Mao M, Chupin S, Chevrollier A, Procaccio V, Bonneau D, Logan DC, Reynier P, Lenaers G, Khiati S (2017) CLUH couples mitochondrial distribution to the energetic and metabolic status. Journal of Cell Science, 130, 1940-1951.


  • Antonio C, Päpke C, Rocha M, Diab H, Limami AM, Obata T, Fernie AR, van Dongen JT. (2016) Regulation of primary metabolism in response to low oxygen availability as revealed by carbon and nitrogen isotope redistribution. Plant Physiology 170: 43-56.
  • Bobille H, Limami AM, Robins RJ, Cukier C, Le Floch G, Fustec J. (2016) Evolution of the amino acid fingerprint in the unsterilized rhizosphere of a legume in relation to plant maturity. Soil Biology and Biochemistry 101: 226-236.
  • Dell’Aglio E, Salvi D, Kraut A, Baudet M, Macherel D, Neveu M, Ferro M, Curien G, Rolland D (2016) No plastidial calmodulin-like proteins detected by two targeted mass-spectrometry approaches and GFP fusion proteins. New Negatives in Plant Science, 3: 19-26.
  • Diab H, Limami AM. (2016) Reconfiguration of N Metabolism upon Hypoxia Stress and Recovery: Roles of Alanine Aminotransferase (AlaAT) and Glutamate Dehydrogenase (GDH). Plants 5(2): 5.
  • Dumas AN, Taconnat L, Barbas E, Rigaill G, Catrice O, Bernard D,  Benamar A, Macherel D, El Amrani A, Berthomé R (2016) Unraveling the early molecular and physiological mechanisms involved in response to phenanthrene exposure. BMC Genomics, 17: 818.
  • Jaspard E, Hunault G (2016)  sHSPdb: a database for the analysis of small Heat Shock Proteins. BMC Plant Biology, 16: 135.
  • Slama I, Jdey A, Rouached A, Talbi O, Debez A, Ghnaya T, Limami AM, Abdelly C. (2016) Comparative responses to water deficit stress and subsequent recovery in the cultivated beet Beta vulgaris and its wild relative B. macrocarpa. Crop and Pasture Science 67: 553-562.
  • Youssef C, Aubry C, Montrichard F, Beucher D, Juchaux M, Ben C, Prosperi JM, Teulat B. (2016) Cell length instead of cell number becomes the predominant factor contributing to hypocotyl length genotypic differences under abiotic stress in Medicago truncatula. Physiologia Plantarum 156: 108-124.


  • Allorent G, Osorio S, Ly Vu J, Falconet D, Jouhet J, Kuntz M, R. Fernie AR, Lerbs-Mache S, Macherel D, Courtois F, Finazzi G (2015) Adjustments of embryonic photosynthetic activity modulate seed fitness in Arabidopsis thalianaNew Phytologist, 205: 707-719.
  • Avelange-Macherel M-H,  Payet N, Lalanne D, Neveu M, Tolleter D, Burstin J, Macherel D. (2015) Variability within a pea core collection of LEAM and HSP22, two mitochondrial seed proteins involved in stress tolerance. Plant, Cell and Environment 38: 1299-1311.
  • Calmes B, Nguyen G, Dumur J, Agusti-Brisach C, Campion C, Iacomi B, Pigné S, Dias E, Macherel D, Guillemette T, Simoneau P (2015) Glucosinolate-derived isothiocyanates impact mitochondrial function in fungal cells and elicit an oxidative stress response necessary for growth recovery. Frontiers in Plant Science, 6, 414.
  • Ekanayake SB, El Zawily AM, Paszkiewicz G, Rolland A, Logan DC (2015) Imaging and analysis of mitochondrial dynamics in living cells. In "Plant Mitochondria, Methods and protocols", Methods in Molecular Biology 1305, Springer protocols, Whelan J & Murchia M.W. eds, ISBN 978-1-4939-2639-8.
  • Lahaye M, Falourd X, Limami A, Foucat L. (2015) Water mobility and microstructure evolution in the germinating Medicago truncatula seed by NMR relaxometry. A revisited interpretation of multicomponent relaxation. Journal of Agricultural and Food Chemistry 63: 1698-1710.
  • Pellizzaro A, Clochard T, Planchet E, Limami AM, Morère-Le Paven MC. (2015) Identification and molecular characterization of Medicago truncatula NRT2 and NAR2 families. Physiologia Plantarum 154: 256-269.
  • Planchet E, Limami AM. (2015) Amino acid synthesis under abiotic stress. In D'Mello J.P.F (ed), Amino acids in higher plants, p. 262-276, DOI: 10.1079/9781780642635.0262; CAB International, Wallingford, UK.
  • Sechet J, Roux C, Plessis A, Effroy D, Frey A, Perreau F, Krieger-Liszkay A, Macherel D, North HM, Mireau H, Marion-Poll A (2015) The ABA-deficiency suppressor locus HAS2 encodes the PPR protein LOI1/MEF11 involved in mitochondrial RNA editing. Molecular Plant, 8, 644-656.
  • Wagner S, Smrutisanjita B, De Bortoli S, Logan DC, Fuchs P, Carraretto L, Teardo E, Cendron L, Nietzel T, Fubl M, Doccula FG, Navazio L, Fricker MD, Van Aken O, Finkemeier I, Meyer AJ, Szabo I, Costa A, Schwarzlander M (2015) The EF-hand Ca2+ binding protein MICU choreographs mitochondrial Ca2+ dynamics in Arabidopsis. The Plant Cell, 27, 3190-3212.


  • Candat A, Paszkiewicz G, Neveu M, Gautier R, Logan DC, Avelange-Macherel MH, Macherel D. (2014) The ubiquitous distribution of LEA proteins across cell compartments offers tailored protection against abiotic stress. The Plant Cell, 26, 3148-3166.
  • Chentli A, Gillmann L, Bouazza L, Medjkal S, Limami AM, Morère-Le Paven M-C, Bousseboua H. (2014) Effects of secondary compounds from cactus and acacias trees on rumen microbial profile changes performed by Real-Time PCR. International Journal of Advanced Research 2: 660-671.
  • Dahan J, Tcherkez G, Macherel D, Benamar A, Belcram K1, Quadrado M, Arnal N, Mireau H (2014) Disruption of the CYTOCHROME C OXIDASE DEFICIENT 1 gene leads to cytochrome c oxidase depletion and reorchestrated respiratory metabolism in Arabidopsis thaliana. Plant Physiology, 166, 1788-1802.
  • El Zawily AM, Schwarzländer M, Finkemeier I, Johnston IG, Benamar A, Cao Y, Gissot C, Meyer AJ, Wilson K, Datla R, Macherel D, Jones NS, Logan DC (2014) FRIENDLY regulates mitochondrial distribution, fusion, and quality control in Arabidopsis. Plant Physiology, 166, 808-828.
  • Jaspard E, Hunault G (2014) Comparison of amino acids, physico-chemical properties and usage of late embryogenesis abundant proteins, Hydrophilins and WHy Domain. PLoS One. 9, e109570.
  • Larrainzar E, Molenaar JA, Wienkoop S, Gil-Quintana E, Alibert B, Limami AM, Arrese-Igor C, González EM. (2014) Drought stress provokes the down-regulation of methionine and ethylene biosynthesis pathways in Medicago truncatula roots and nodules. Plant, Cell and Environment 37: 2051-2063.
  • Léran S, Varala K, Boyer J-C, Chiurazzi M, Crawford N, Daniel-Vedèle F, David L, Dickstein R, Fernandez E, Forde B, Gassmann W, Geiger D, Gojon A, Gong J-M, Halkier BA, Harris JM, Hedrich R, Limami AM, Rentsch D, Seo M, Tsay Y-F, Zhang M, Coruzzi G, Lacombe B. (2014) A unified nomenclature of NITRATE TRANSPORTER 1 / PEPTIDE TRANSPORTER family members in plants. Trends in Plant Science 19: 5-9.
  • Limami AM. (2014) Adaptations of nitrogen metabolism to oxygen deprivation in plants. In Low-Oxygen Stress in Plants, Plant Cell Monographs 21 (Eds: van Dongen JT and Licausi F), DOI 10.1007/978-3-7091-1254-0 11; Springer-Verlag, Wien.
  • Limami AM, Diab H, Lothier J. (2014). Nitrogen metabolism in plants under low oxygen stress. Planta 239: 531-541.
  • Pellizzaro A, Clochard T, Cukier C, Bourdin C, Juchaux M, Montrichard F, Thany S, Raymond V, Planchet E, Limami AM, Morère-Le Paven MC. (2014) The nitrate transporter MtNPF6.8 (MtNRT1.3) transports ABA and mediates nitrate regulation of primary root growth in Medicago truncatula. Plant Physiology 166: 2152-2165.
  • Pierre J, Teulat B, Juchaux M, Mabileau G, Demilly D, Dürr C. (2014). Cellular changes during Medicago truncatula hypocotyl growth depend on temperature and genotype. Plant Science 217-218:18-26.
  • Planchet E, Verdu I, Delahaie J, Cukier C, Girard C, Morère-Le Paven MC, Limami AM. (2014) Abscisic acid-induced nitric oxide and proline accumulation in independent pathways under water deficit stress during seedling establishment in Medicago truncatula. Journal of Experimental Botany 65: 2161-2170.
  • Schwarzländer M, Wagner S, Ermakova YG, Belousov VV, Radi R, Beckman JS, Buettner GR, Demaurex N, Duchen MR, Forman HJ, Fricker MD, Gems D, Halestrap AP, Halliwell B, Jakob U, Johnston IG, Jones NS, Logan DC, Morgan B, Müller FL, Nicholls DG, Remington SJ, Schumacker PT, Winterbourn CC, Sweetlove LJ, Meyer AJ, Dick TP, Murphy MP (2014) The 'mitoflash' probe cpYFP does not respond to superoxide. Nature, 574, E12-E14.


  • Benamar A, Pierart A, Baecker V, Avelange-Macherel MH,  Rolland A, Gaudichon S, di Gioia L, Macherel D. (2013) A simple system using natural mineral water for high-throughput phenotyping of Arabidopsis thaliana seedlings in liquid culture. International Journal of High-throughput Screening, 4: 1-15.
  • Benarbia MA, Macherel D, Faure S, Jaques C, Andriantsitohaina R, Malthiery Y. (2013) Plasmatic concentration of organochlorine lindane acts as metabolic disruptors in HepG2 liver cell line by inducing mitochondrial disorder. Toxicology and Applied Pharmacology, 272: 325-332.
  • Candat A, Poupart P, Andrieu JP, Chevrollie A,  Reynier P, Rogniaux H, Avelange-Macherel MH,  Macherel D. (2013) Experimental determination of organelle targeting peptide cleavage sites using transient expression of GFP translational fusions. Analytical Biochemistry, 434: 44-51.
  • Charrier A, Lelièvre E, Limami AM, Planchet E. (2013) Medicago truncatula stress associated protein 1 gene (MtSAP1) overexpression confers tolerance to abiotic stress and impacts proline accumulation in transgenic tobacco. Journal of Plant Physiology 170: 874-877
  • Chatelain E, Satour P, Laugier E, Ly Vu B, Payet N, Rey P, Montrichard F. (2013) Evidence for participation of the methionine sulfoxide reductase repair system in plant seed longevity. Proc. Natl. Acad. Sci. USA 110: 3633-3638.
  • Diab H, Cukier C. (2013) Impact of waterloging-induced hypoxia on nitrogen metabolism in the legume Medicago truncatula. International Journal of Life Sciences Biotechnology and Pharma Research 2: 401-409.
  • Macherel D. (2013) We become more aware of the void as we explore it. New Phytologist, 199: 873-875.
  • Macherel D, Jaspard E, Candat A, Hunault G, Poupart P, Rolland A, Benamar A, Avelange-Macherel MH. (2013) Why so many LEA proteins? Cryobiology and Cryotechnology, 59(1):35-39.
  • Rouached A, Slama I, Zorrig W, Jdeya A, Cukier C, Rabhi M, Talbi O, Limami AM, Abdelly C. (2013). Differential performance of two forage species: Medicago truncatula and Sulla carnosa under water deficit stress and recovery. Crop and Pasture Sciences 64: 254-264.


  • Charrier A, Planchet E, Cerveau D, Gimeno-Gilles C, Verdu I, Limami AM, Lelievre E. (2012) Overexpression of a Medicago truncatula Stress Associated Protein gene (MtSAP1) leads to nitric oxide accumulation and confers osmotic and salt stress tolerance in transgenic tobacco. Planta 236: 567-577.
  • Jaspard E., Macherel D., Hunault G. (2012) Computational and statistical analyses ofamino acid usage and physico-chemical properties of the twelve late embryogenesis abundant protein classes. PloS One, 7: e36968.
  • Lechat M-M., Pouvreau J-B., Thoiron S.,  Péron T., Gauthier M., Montiel G., Véronési C., Todoroki Y., Monteau F., Macherel D., Simier P., Delavault P. (2012) PrCYP707A1, an ABA catabolic gene, is a key component of Phelipanche ramosa seed germination in response to the strigolactone analog GR24. Journal of Experimental Botany, 63: 5311-5322.
  • Ren M, Venglat P, Qiu S, Feng L, Cao Y, Wang E, Xiang D, Wang J, Alexander D, Chalivendra S, Logan D, Mattoo A, Selvaraj G, Datla R. (2012) Target of rapamycin signaling regulates metabolism, growth, and life span in Arabidopsis. The Plant Cell,  24: 4850-4874.
  • Schwarzländer M, Logan DC, Johnston IG, Jones NS, Meyer AJ, Fricker MD, Sweetlove LJ (2012) Pulsing of membrane potential in individual mitochondria: a stress-induced mechanism to regulate respiratory bioenergetics in Arabidopsis. ThePlant Cell 24: 1188-1201.
  • Schwarzländer M., Murphy M.P.,  Duchen M.R., Logan D.C., Fricker M.D., Halestrap A.P., Müller F.L., Rizzuto R., Dick T.P., Meyer A.J., Sweetlove L.J. (2012) Mitochondrial ‘flashes’: a radical concept repHined. Trends in Cell Biology, 22: 503-508.
  • Zoumarou-Wallis N, Teulat-Merah B, Zinsou V, Ben Salem M, Rhoma S (2012) Detection of the Quantitative Trait Locus (QTL) involved in the resistance of barley (Hordeum vulgare L.) to the mildew under different water treatments, in semi-arid Mediterranean region. International Journal of Science and Advanced Technology, 2: 136–143.


  • Dias PMB, Brunel S, Wagner MH, Huguet T, Prospéri J.M, Dürr C, Teulat-Merah B (2011) QTL analyses of germination and pre-emergence growth at extreme temperatures in Medicago truncatula.Theoretical Applied Genetics 122:429-444.
  • Gimeno-Gilles C, Gervais ML, Planchet E, Satour P, Limami AM, Lelievre E. (2011) A stress-associated protein containing A20/AN1 zing-finger domains expressed in Medicago truncatula seeds. Plant Physiology and Biochemistry 49: 303-310.
  • Kaiser WM, Planchet E, Rümer S. (2011) Nitrate reductase and nitric oxide. In Annual Plant reviews, Nitrogen metabolism in plants in the post-genomic era (Eds: Foyer C and Zhang H), 42: 127-145, DOI: 10.1002/9781444328608.ch6; Wiley-Blackwell, Oxford, UK.
  • Morère-Le Paven MC, Viau L, Hamon A, Vandecasteele C, Pellizzaro A, Bourdin C, Laffont C, Lapied B, Lepetit M, Frugier F, Legros C, Limami AM. (2011)  Characterization of a dual affinity nitrate transporter MtNRT1.3 in the model legume Medicago truncatula. Journal of Experimental Botany 62: 5595–5605.
  • Planchet E, Rannou O, Ricoult C, Limami AM. (2011) Unravelling the involvement of ABA in the water deficit-induced modulation of nitrogen metabolism in Medicago truncatula seedlings. Plant Signaling & Behavior 6: 1074-1076.
  • Planchet E, Rannou O, Ricoult C, Boutet-Mercey S, Maia-Grondard A, Limami AM. (2011) Nitrogen metabolism responses to water deficit act through both abscisic acid (ABA)-dependent and independent pathways in Medicago truncatula during post-germination. Journal of Experimental Botany 62: 605-615.
  • Renard M, Alkhalfioui F, Schmitt-Keichinger C, Ritzenthaler, Montrichard F (2011) Identification and characterization of thioredoxin h isoforms differentially expressed in germinating seeds of the model legume Medicago truncatula. Plant Physiology 155:1113-1126.
  • Teulat-Merah B, Morère-Le Paven MC, Ricoult C, Aubry C, Peltier D. (2011) cDNA-AFLP profiling in embryonic axes during the germination time-course has allowed to identify mRNAs associated with early radicle growth in common bean. Biologia Plantarum 55: 437-447.
  • Vandecasteele C, Teulat-Merah B, Morère-Le Paven MC, Leprince O, Ly Vu B, Viau L, Ledroit L, Pelletier S, Payet N, Satour P, Lebras C, Gallardo K, Huguet T, Limami AM, Prosperi JM, Buitink J. (2011) QTL analysis reveals a correlation between the ratio of sucrose/raffinose family oligosaccharides and seed vigour in Medicago truncatula. Plant, Cell and Environment 34: 1473-1487.


  • Bolingue W, Rosnoblet C, Ly Vu B, Leprince O, Aubry C, Buitink J (2010) The MtSNF4b subunit of the sucrose non-fermenting-related kinase complex connects after-ripening and constitutive defense responses in seeds of Medicago truncatula. Plant Journal 61:792-803.
  • Cassan L, Moreau L, Segouin S, Bellamy A, Falque M, Limami AM. (2010) Genetic map construction and quantitative trait loci (QTL) mapping for nitrogen use efficiency and its relationship with productivity and quality of the biennial crop Belgian endive (Cichorium intybus L.). Journal of Plant Physiology 167: 1253–1263.
  • Hunault G., Jaspard E. (2010) LEAPdb: a database for the late embryogenesis abundant proteins. BMC Genomics 11, 221.
  • Tolleter D, Hincha DK, Macherel D (2010) A mitochondrial late embryogenesis abundant protein stabilizes model membranes in the dry state. BBA Biomembranes, 1798, 1926-33.
  • Tunnacliffe A., Hincha D.K., Leprince O, Macherel D. (2010) LEA proteins: versatility of forms and function. Lubzens, E., Cerda, J. and M. Clark. Eds. Dormancy and Resistance in Harsh Environments. Topics in Current Genetics, Springer, pp. 91-108.